Runes have many varieties (eg. Battle, Life, Bulwark, Precision etc.) and they all have different available stats. Many funds have a special passive trait, though some gain a random one.
Rune Types
Rune
Stats available
Bonus stat
Craftable?
Restrictions
Arcane
20% chance to apply a random debuff on basic attacks
No
Arcane heroes only
Assassin
20% chance to apply Off-Balance on basic attacks
No
Assassins only
Battle
Random
Yes
None
Bulwark
Random
Yes
None
Caster
20% chance to purge a buff on hit
No
None
Corruption
[Random]% chance to Disease on basic attacks
Yes
None
Demon
Deals additional 10% damage for every debuff on the target enemy
No
Demons only
Dodge
Evading
No
Dragon
20% chance to apply Doom on basic attacks
No
Dragons only
Enabler
25% chance to make an Epic attack (stacks)
No
Epic Heroes only
Hero
No
None
Life
Hp, ?
Random
Yes
None
Ogre
20% chance to lower enemy ATK on a basic attack
No
Ogres only
Planning
Gain bonus Hero XP in PvE
Yes
None
Plant
20% chance to reflect damage back at melee attackers
No
Plants only
Precision
Crit, ?
Random
Yes
None
Reptile
15% chance to Stone on basic attacks
No
Reptiles only
Unbreakable Heart
Once per dungeon, survives first death blow, and health drops to 1 instead (effect stacks)
No
None
Warrior
20% chance for an extra basic attack (chances stack)